The small molecule, genistein, increases hepcidin expression in human hepatocytes

The small molecule, genistein, increases hepcidin expression in human hepatocytes

Hepcidin, a peptide hormone that decreases intestinal iron absorption and macrophage iron release, is a potential drug target for patients with iron overload syndromes because its levels are inappropriately low in these individuals. Endogenous stimulants of Hepcidin transcription include bone morpho...

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Bibliographic Details
Main Authors: Zhen, Aileen W., Nguyen, Nancy H., Gibert, Yann, Motola, Shmulik, Buckett, Peter, Wessling-Resnick, Marianne, Fraenkel, Ernest, Fraenkel, Paula G.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2014
Online Access:http://hdl.handle.net/1721.1/88912
https://orcid.org/0000-0001-9249-8181

Internet

http://hdl.handle.net/1721.1/88912
https://orcid.org/0000-0001-9249-8181

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