Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis

Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis

As principal degrading enzymes of the extracellular matrix, metalloproteinases (MPs) contribute to various pathologies and represent a family of promising drug targets and biomarker candidates. However, multiple proteases and endogenous inhibitors interact to govern MP activity, often leading to hig...

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Bibliographic Details
Main Authors: Chen, Chia-Hung, Sarkar, Aniruddh, Beste, Michael T., Isaacson, Keith B., Lauffenburger, Douglas A., Griffith, Linda G., Han, Jongyoon, Miller, Miles Aaron
Other Authors: Massachusetts Institute of Technology. Center for Gynepathology Research
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2014
Online Access:http://hdl.handle.net/1721.1/88925
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0001-7215-1439

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