The Receptor AXL Diversifies EGFR Signaling and Limits the Response to EGFR-Targeted Inhibitors in Triple-Negative Breast Cancer Cells

The relationship between drug resistance, changes in signaling, and emergence of an invasive phenotype is well appreciated, but the underlying mechanisms are not well understood. Using machine learning analysis applied to the Cancer Cell Line Encyclopedia database, we identified expression of AXL, t...

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Detalhes bibliográficos
Main Authors: Meyer, Aaron Samuel, Miller, Miles Aaron, Gertler, Frank, Lauffenburger, Douglas A
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: American Association for the Advancement of Science (AAAS) 2014
Acesso em linha:http://hdl.handle.net/1721.1/88954
https://orcid.org/0000-0003-3214-4554

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