Enhanced ex vivo expansion of adult mesenchymal stem cells by fetal mesenchymal stem cell ECM

Large-scale expansion of highly functional adult human mesenchymal stem cells (aMSCs) remains technologically challenging as aMSCs lose self renewal capacity and multipotency during traditional long-term culture and their quality/quantity declines with donor age and disease. Identification of cultur...

Full description

Bibliographic Details
Main Authors: Ng, Chee Ping, Mohamed Sharif, Abdul Rahim, Heath, Daniel E., Chow, John W., Zhang, Claire BY., Chan-Park, Mary B., Hammond, Paula T., Chan, Jerry K. Y., Griffith, Linda G.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/88963
https://orcid.org/0000-0002-1801-5548