Chinese hamster ovary cells can produce galactose-α-1,3-galactose antigens on proteins

Chinese hamster ovary cells can produce galactose-α-1,3-galactose antigens on proteins

Chinese hamster ovary (CHO) cells are widely used for the manufacture of biotherapeutics, in part because of their ability to produce proteins with desirable properties, including 'human-like' glycosylation profiles. For biotherapeutics production, control of glycosylation is critical beca...

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Bibliographic Details
Main Authors: Bosques, Carlos J., Collins, Brian E., Meador, James W., Sarvaiya, Hetal, Murphy, Jennifer L., DelloRusso, Guy, Bulik, Dorota A., Hsu, I-Hsuan, Washburn, Nathaniel, Sipsey, Sandra F., Myette, James R., Raman, Rahul, Sasisekharan, Ram, Venkataraman, Ganesh, Shriver, Zachary H.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/89032
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840

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