Connecting the study of wild influenza with the potential for pandemic disease
Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organizatio...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Elsevier
2014
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| Online Access: | http://hdl.handle.net/1721.1/89052 https://orcid.org/0000-0002-6747-7765 https://orcid.org/0000-0003-3213-6693 |
| _version_ | 1826215078642319360 |
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| author | Runstadler, Jonathan Keogh, Mandy Hill, Nichola J. Hussein, Islam Puryear, Wendy Blay |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Runstadler, Jonathan Keogh, Mandy Hill, Nichola J. Hussein, Islam Puryear, Wendy Blay |
| author_sort | Runstadler, Jonathan |
| collection | MIT |
| description | Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host–virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains. |
| first_indexed | 2024-09-23T16:16:11Z |
| format | Article |
| id | mit-1721.1/89052 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T16:16:11Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/890522022-09-29T19:15:50Z Connecting the study of wild influenza with the potential for pandemic disease Runstadler, Jonathan Keogh, Mandy Hill, Nichola J. Hussein, Islam Puryear, Wendy Blay Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Division of Comparative Medicine Runstadler, Jonathan Hill, Nichola J. Hussein, Islam Puryear, Wendy Blay Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host–virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains. National Institute of Allergy and Infectious Diseases (U.S.) (Contract HHSN266200700010C) Massachusetts Institute of Technology 2014-08-26T13:57:54Z 2014-08-26T13:57:54Z 2013-03 2013-02 Article http://purl.org/eprint/type/JournalArticle 15671348 http://hdl.handle.net/1721.1/89052 Runstadler, Jonathan, Nichola Hill, Islam T.M. Hussein, Wendy Puryear, and Mandy Keogh. “Connecting the Study of Wild Influenza with the Potential for Pandemic Disease.” Infection, Genetics and Evolution 17 (July 2013): 162–187. https://orcid.org/0000-0002-6747-7765 https://orcid.org/0000-0003-3213-6693 en_US http://dx.doi.org/10.1016/j.meegid.2013.02.020 Infection, Genetics and Evolution Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Elsevier PMC |
| spellingShingle | Runstadler, Jonathan Keogh, Mandy Hill, Nichola J. Hussein, Islam Puryear, Wendy Blay Connecting the study of wild influenza with the potential for pandemic disease |
| title | Connecting the study of wild influenza with the potential for pandemic disease |
| title_full | Connecting the study of wild influenza with the potential for pandemic disease |
| title_fullStr | Connecting the study of wild influenza with the potential for pandemic disease |
| title_full_unstemmed | Connecting the study of wild influenza with the potential for pandemic disease |
| title_short | Connecting the study of wild influenza with the potential for pandemic disease |
| title_sort | connecting the study of wild influenza with the potential for pandemic disease |
| url | http://hdl.handle.net/1721.1/89052 https://orcid.org/0000-0002-6747-7765 https://orcid.org/0000-0003-3213-6693 |
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