Searching for missing heritability: Designing rare variant association studies

Searching for missing heritability: Designing rare variant association studies

Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and traits, revealing important biological pathways and defining novel therapeutic hypotheses. However, the genes discovered to date typically explain less than half of the apparent heritability. Because effor...

书目详细资料
Main Authors:	Zuk, Or, Schaffner, Stephen F., Samocha, Kaitlin, Do, Ron, Hechter, Eliana, Kathiresan, Sekar, Daly, Mark J., Neale, Benjamin M., Sunyaev, Shamil R., Lander, Eric Steven
其他作者:	Massachusetts Institute of Technology. Department of Biology
格式:	文件
语言:	en_US
出版:	National Academy of Sciences (U.S.) 2014
在线阅读:	http://hdl.handle.net/1721.1/89123

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