MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

Commensal bacterial sensing by Toll-like receptors is critical for maintaining intestinal homeostasis, but can lead to colitis in the absence of interleukin-10. Although Toll-like receptors are expressed in multiple cell types in the colon, the cell type(s) responsible for the development of colitis...

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Bibliographic Details
Main Authors: Hoshi, Namiko, Schenten, Dominik, Nish, Simone A., Walther, Zenta, Gagliani, Nicola, Flavell, Richard A., Reizis, Boris, Shen, Zeli, Fox, James G., Iwasaki, Akiko, Medzhitov, Ruslan
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/89148
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/89148
https://orcid.org/0000-0001-9307-6116

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