Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry

Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry

There is a great need for quantitative assays in measuring proteins. Traditional sandwich immunoassays, largely considered the gold standard in quantitation, are associated with a high cost, long lead time, and are fraught with drawbacks (e.g. heterophilic antibodies, autoantibody interference, ...

Full description

Bibliographic Details
Main Authors: Zhao, Lei, Whiteaker, Jeffrey R., Pope, Matthew E., Kuhn, Eric, Jackson, Angela, Anderson, N. Leigh, Pearson, Terry W., Paulovich, Amanda G., Carr, Steven A
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: MyJoVE Corporation 2014
Online Access:http://hdl.handle.net/1721.1/89657
https://orcid.org/0000-0002-7203-4299

Internet

http://hdl.handle.net/1721.1/89657
https://orcid.org/0000-0002-7203-4299

Similar Items