Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

Bibliografski detalji
Glavni autori:	Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S
Daljnji autori:	Harvard University--MIT Division of Health Sciences and Technology
Format:	Članak
Jezik:	en_US
Izdano:	Royal Society of Chemistry 2014
Online pristup:	http://hdl.handle.net/1721.1/91143 https://orcid.org/0000-0002-2100-1171 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492

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