Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

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Détails bibliographiques
Auteurs principaux: Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S
Autres auteurs: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Langue:en_US
Publié: Royal Society of Chemistry 2014
Accès en ligne:http://hdl.handle.net/1721.1/91143
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492

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