Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles
One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...
Main Authors: | Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry
2014
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Online Access: | http://hdl.handle.net/1721.1/91143 https://orcid.org/0000-0002-2100-1171 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492 |
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