Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S
Kolejni autorzy:	Harvard University--MIT Division of Health Sciences and Technology
Format:	Artykuł
Język:	en_US
Wydane:	Royal Society of Chemistry 2014
Dostęp online:	http://hdl.handle.net/1721.1/91143 https://orcid.org/0000-0002-2100-1171 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492

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