Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

書目詳細資料
Main Authors:	Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S
其他作者:	Harvard University--MIT Division of Health Sciences and Technology
格式:	Article
語言:	en_US
出版:	Royal Society of Chemistry 2014
在線閱讀:	http://hdl.handle.net/1721.1/91143 https://orcid.org/0000-0002-2100-1171 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492

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