Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles
One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...
Автори: | Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S |
---|---|
Інші автори: | Harvard University--MIT Division of Health Sciences and Technology |
Формат: | Стаття |
Мова: | en_US |
Опубліковано: |
Royal Society of Chemistry
2014
|
Онлайн доступ: | http://hdl.handle.net/1721.1/91143 https://orcid.org/0000-0002-2100-1171 https://orcid.org/0000-0001-5629-4798 https://orcid.org/0000-0003-4255-0492 |
Схожі ресурси
Схожі ресурси
-
FRET-Labeled siRNA Probes for Tracking Assembly and Disassembly of siRNA-Nanocomplexes
за авторством: Alabi, Christopher A., та інші
Опубліковано: (2013) -
Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery
за авторством: Alabi, Christopher A., та інші
Опубліковано: (2014) -
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
за авторством: Sahay, Gaurav, та інші
Опубліковано: (2014) -
Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles
за авторством: Castillo, Betzaida, та інші
Опубліковано: (2013) -
Alkane-modified short polyethyleneimine for siRNA delivery
за авторством: Anderson, Daniel, та інші
Опубліковано: (2017)