Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles

One important barrier facing the delivery of short interfering RNAs (siRNAs) via synthetic nanoparticles is the rate of nanoparticle disassembly. However, our ability to optimize the release kinetics of siRNAs from nanoparticles for maximum efficacy is limited by the lack of methods to track their i...

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מידע ביבליוגרפי
Main Authors: Alabi, Christopher A., Sahay, Gaurav, Anderson, Daniel Griffith, Langer, Robert S
מחברים אחרים: Harvard University--MIT Division of Health Sciences and Technology
פורמט: Article
שפה:en_US
יצא לאור: Royal Society of Chemistry 2014
גישה מקוונת:http://hdl.handle.net/1721.1/91143
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492

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