The Membrane Environment Can Promote or Suppress Bistability in Cell Signaling Networks
Many key biochemical reactions that mediate signal transduction in cells occur at the cell membrane, yet how the two-dimensional membrane environment influences the collective behavior of signaling networks is poorly understood. We study models of two topologically different signaling pathways that...
Main Authors: | Abel, Steven M., Roose, Jeroen P., Groves, Jay T., Weiss, Arthur, Chakraborty, Arup K |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2014
|
Online Access: | http://hdl.handle.net/1721.1/91216 https://orcid.org/0000-0003-1268-9602 |
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