Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Despite efforts to understand the interactions between nanoparticles and cells, the cellular processes that determine the efficiency of intracellular drug delivery remain unclear. Here we examine cellular uptake of short interfering RNA (siRNA) delivered in lipid nanoparticles (LNPs) using cellular...

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Detalles Bibliográficos
Main Authors: Sahay, Gaurav, Querbes, William, Alabi, Christopher A., Eltoukhy, Ahmed A., Sarkar, Sovan, Zurenko, Christopher, Karagiannis, Emmanouil, Love, Kevin T., Chen, Delai, Zoncu, Roberto, Buganim, Yosef, Schroeder, Avi, Langer, Robert, Anderson, Daniel Griffith
Outros autores: Massachusetts Institute of Technology. Department of Chemical Engineering
Formato: Artigo
Idioma:en_US
Publicado: 2014
Acceso en liña:http://hdl.handle.net/1721.1/91243
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0003-0131-6552
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/91243
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0003-0131-6552
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492

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