Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Despite efforts to understand the interactions between nanoparticles and cells, the cellular processes that determine the efficiency of intracellular drug delivery remain unclear. Here we examine cellular uptake of short interfering RNA (siRNA) delivered in lipid nanoparticles (LNPs) using cellular...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Sahay, Gaurav, Querbes, William, Alabi, Christopher A., Eltoukhy, Ahmed A., Sarkar, Sovan, Zurenko, Christopher, Karagiannis, Emmanouil, Love, Kevin T., Chen, Delai, Zoncu, Roberto, Buganim, Yosef, Schroeder, Avi, Langer, Robert, Anderson, Daniel Griffith
Eará dahkkit: Massachusetts Institute of Technology. Department of Chemical Engineering
Materiálatiipa: Artihkal
Giella:en_US
Almmustuhtton: 2014
Liŋkkat:http://hdl.handle.net/1721.1/91243
https://orcid.org/0000-0002-2100-1171
https://orcid.org/0000-0003-0131-6552
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0003-4255-0492