A nanofluidic device for single molecule studies with in situ control of environmental solution conditions
We report an approach to study the in situ conformational response of single biomolecules such as DNA to a change in environmental solution conditions. These conditions are, for example, the composition of the buffer or the presence of protein. For this purpose, we designed and fabricated a nanoflui...
Main Authors: | Zhang, Ce, Jiang, Kai, Liu, Fan, Doyle, Patrick S., van Kan, Jeroen A., van der Maarel, Johan R. C. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry, The
2014
|
Online Access: | http://hdl.handle.net/1721.1/91270 |
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