Fabrication of a Hybrid Microfluidic System Incorporating both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network

A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With t...

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Bibliografische gegevens
Hoofdauteurs: Bellan, Leon M., Kniazeva, Tatiana, Kim, Ernest S., Epshteyn, Alla A., Cropek, Donald M., Borenstein, Jeffrey T., Langer, Robert S
Andere auteurs: Charles Stark Draper Laboratory
Formaat: Artikel
Taal:en_US
Gepubliceerd in: Wiley-VCH Verlag GmbH & Co. 2014
Online toegang:http://hdl.handle.net/1721.1/91502
https://orcid.org/0000-0003-4255-0492
Omschrijving
Samenvatting:A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.