Flow-Through Comb Electroporation Device for Delivery of Macromolecules

We present a microfluidic electroporation device with a comb electrode layout fabricated in polydimethylsiloxane (PMDS) and glass. Characterization experiments with HeLa cells and fluorescent dextran show efficient delivery (~95%) with low toxicity (cell viability ~85%) as well as rapid pore closure...

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Bibliographic Details
Main Authors: Adamo, Andrea, Arione, Alessandro, Sharei, Armon Reza, Jensen, Klavs F
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2014
Online Access:http://hdl.handle.net/1721.1/91542
https://orcid.org/0000-0001-7192-580X

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