Interrogating Signaling Nodes Involved in Cellular Transformations Using Kinase Activity Probes
Protein kinases catalyze protein phosphorylation and thereby control the flow of information through signaling cascades. Currently available methods for concomitant assessment of the enzymatic activities of multiple kinases in complex biological samples rely on indirect proxies for enzymatic activit...
Main Authors: | Stains, Cliff I., Tedford, Nathan C., Walkup, Traci C., Lukovic, Elvedin, Goguen, Brenda N., Griffith, Linda G., Lauffenburger, Douglas A., Imperiali, Barbara |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
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Online Access: | http://hdl.handle.net/1721.1/91552 https://orcid.org/0000-0002-5749-7869 https://orcid.org/0000-0002-1801-5548 |
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