Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells

Supported lipid bilayers are an important biomolecular tool for characterizing immunological synapses. Immobilized bilayers presenting tethered ligands on planar substrates have yielded both spatio-temporal and structural insights into how T cell receptors (TCRs) reorganize during the initial format...

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Bibliographic Details
Main Authors: Torres, Alexis J., Contento, Rita Lucia, Gordo, Susana, Wucherpfennig, Kai W., Love, John C
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2014
Online Access:http://hdl.handle.net/1721.1/91597
https://orcid.org/0000-0001-8599-9295
https://orcid.org/0000-0003-0921-3144