Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells
Supported lipid bilayers are an important biomolecular tool for characterizing immunological synapses. Immobilized bilayers presenting tethered ligands on planar substrates have yielded both spatio-temporal and structural insights into how T cell receptors (TCRs) reorganize during the initial format...
Main Authors: | Torres, Alexis J., Contento, Rita Lucia, Gordo, Susana, Wucherpfennig, Kai W., Love, John C |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry
2014
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Online Access: | http://hdl.handle.net/1721.1/91597 https://orcid.org/0000-0001-8599-9295 https://orcid.org/0000-0003-0921-3144 |
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