Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles
Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order n...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | en_US |
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Wiley Blackwell
2014
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| Online Access: | http://hdl.handle.net/1721.1/91600 https://orcid.org/0000-0003-3988-0837 |
| _version_ | 1826202742837739520 |
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| author | Herlihy, Kevin P. Deng, Zhou J. Chu, Kevin S. Bowerman, Charles J. DeSimone, Joseph M. Morton, Stephen Winford Shopsowitz, Kevin Hammond, Paula T |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Herlihy, Kevin P. Deng, Zhou J. Chu, Kevin S. Bowerman, Charles J. DeSimone, Joseph M. Morton, Stephen Winford Shopsowitz, Kevin Hammond, Paula T |
| author_sort | Herlihy, Kevin P. |
| collection | MIT |
| description | Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery. |
| first_indexed | 2024-09-23T12:16:53Z |
| format | Article |
| id | mit-1721.1/91600 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:16:53Z |
| publishDate | 2014 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/916002022-10-01T08:52:06Z Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles Herlihy, Kevin P. Deng, Zhou J. Chu, Kevin S. Bowerman, Charles J. DeSimone, Joseph M. Morton, Stephen Winford Shopsowitz, Kevin Hammond, Paula T Massachusetts Institute of Technology. Department of Chemical Engineering Koch Institute for Integrative Cancer Research at MIT Morton, Stephen Winford Shopsowitz, Kevin Deng, Zhou J. Hammond, Paula T. Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery. National Cancer Institute (U.S.) (Center for Cancer Nanotechnology Excellence Grant 5 U54 CA151884-02) National Science Foundation (U.S.). Graduate Research Fellowship Natural Sciences and Engineering Research Council of Canada (Postdoctoral Fellowship) 2014-11-17T19:26:40Z 2014-11-17T19:26:40Z 2013-07 2013-05 Article http://purl.org/eprint/type/JournalArticle 09359648 1521-4095 http://hdl.handle.net/1721.1/91600 Morton, Stephen W., Kevin P. Herlihy, Kevin E. Shopsowitz, Zhou J. Deng, Kevin S. Chu, Charles J. Bowerman, Joseph M. DeSimone, and Paula T. Hammond. “Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles.” Advanced Materials 25, no. 34 (July 1, 2013): 4707–4713. https://orcid.org/0000-0003-3988-0837 en_US http://dx.doi.org/10.1002/adma.201302025 Advanced Materials Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Herlihy, Kevin P. Deng, Zhou J. Chu, Kevin S. Bowerman, Charles J. DeSimone, Joseph M. Morton, Stephen Winford Shopsowitz, Kevin Hammond, Paula T Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title | Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title_full | Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title_fullStr | Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title_full_unstemmed | Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title_short | Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles |
| title_sort | scalable manufacture of built to order nanomedicine spray assisted layer by layer functionalization of print nanoparticles |
| url | http://hdl.handle.net/1721.1/91600 https://orcid.org/0000-0003-3988-0837 |
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