CD8[superscript +] T-cell Responses Rapidly Select for Antigen-Negative Tumor Cells in the Prostate

Stimulation of patients' immune systems for the treatment of solid tumors is an emerging therapeutic paradigm. The use of enriched autologous T cells for adoptive cell therapy or vaccination with antigen-loaded dendritic cells have shown clinical efficacy in melanoma and prostate cancer, respec...

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Detalles Bibliográficos
Main Authors: Bak, S. Peter G., Barnkob, Mike Stein, Wittrup, Karl Dane, Chen, Jianzhu
Outros autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado: American Association for Cancer Research 2014
Acceso en liña:http://hdl.handle.net/1721.1/91603
https://orcid.org/0000-0003-2398-5896
https://orcid.org/0000-0002-5687-6154