A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

Eukaryotic transcription factors (TFs) perform complex and combinatorial functions within transcriptional networks. Here, we present a synthetic framework for systematically constructing eukaryotic transcription functions using artificial zinc fingers, modular DNA-binding domains found within many e...

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Bibliographic Details
Main Authors: Khalil, Ahmad S., Lu, Timothy K., Bashor, Caleb, Ramirez, Cherie L., Pyenson, Nora C., Joung, J. Keith, Collins, James J.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91623
https://orcid.org/0000-0002-9999-6690

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