Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention
Shifts of gaze and shifts of attention are closely linked and it is debated whether they result from the same neural mechanisms. Both processes involve the frontal eye fields (FEF), an area which is also a source of top-down feedback to area V4 during covert attention. To test the relative contribut...
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| Format: | Article |
| Language: | en_US |
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Elsevier
2014
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| Online Access: | http://hdl.handle.net/1721.1/91641 https://orcid.org/0000-0002-5938-4227 |
| _version_ | 1811073523292045312 |
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| author | Gregoriou, Georgia G. Gotts, Stephen J. Desimone, Robert |
| author2 | McGovern Institute for Brain Research at MIT |
| author_facet | McGovern Institute for Brain Research at MIT Gregoriou, Georgia G. Gotts, Stephen J. Desimone, Robert |
| author_sort | Gregoriou, Georgia G. |
| collection | MIT |
| description | Shifts of gaze and shifts of attention are closely linked and it is debated whether they result from the same neural mechanisms. Both processes involve the frontal eye fields (FEF), an area which is also a source of top-down feedback to area V4 during covert attention. To test the relative contributions of oculomotor and attention-related FEF signals to such feedback, we recorded simultaneously from both areas in a covert attention task and in a saccade task. In the attention task, only visual and visuomovement FEF neurons showed enhanced responses, whereas movement cells were unchanged. Importantly, visual, but not movement or visuomovement cells, showed enhanced gamma frequency synchronization with activity in V4 during attention. Within FEF, beta synchronization was increased for movement cells during attention but was suppressed in the saccade task. These findings support the idea that the attentional modulation of visual processing is not mediated by movement neurons. |
| first_indexed | 2024-09-23T09:34:19Z |
| format | Article |
| id | mit-1721.1/91641 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T09:34:19Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/916412022-09-26T12:18:33Z Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention Gregoriou, Georgia G. Gotts, Stephen J. Desimone, Robert McGovern Institute for Brain Research at MIT Desimone, Robert Shifts of gaze and shifts of attention are closely linked and it is debated whether they result from the same neural mechanisms. Both processes involve the frontal eye fields (FEF), an area which is also a source of top-down feedback to area V4 during covert attention. To test the relative contributions of oculomotor and attention-related FEF signals to such feedback, we recorded simultaneously from both areas in a covert attention task and in a saccade task. In the attention task, only visual and visuomovement FEF neurons showed enhanced responses, whereas movement cells were unchanged. Importantly, visual, but not movement or visuomovement cells, showed enhanced gamma frequency synchronization with activity in V4 during attention. Within FEF, beta synchronization was increased for movement cells during attention but was suppressed in the saccade task. These findings support the idea that the attentional modulation of visual processing is not mediated by movement neurons. National Eye Institute (Grant 5R01EY017921) 2014-11-20T14:46:12Z 2014-11-20T14:46:12Z 2012-02 2011-12 Article http://purl.org/eprint/type/JournalArticle 08966273 1097-4199 http://hdl.handle.net/1721.1/91641 Gregoriou, Georgia G., Stephen J. Gotts, and Robert Desimone. “Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 During Attention.” Neuron 73, no. 3 (February 2012): 581–594. © 2012 Elsevier Inc. https://orcid.org/0000-0002-5938-4227 en_US http://dx.doi.org/10.1016/j.neuron.2011.12.019 Neuron Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Elsevier Elsevier |
| spellingShingle | Gregoriou, Georgia G. Gotts, Stephen J. Desimone, Robert Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title | Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title_full | Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title_fullStr | Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title_full_unstemmed | Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title_short | Cell-Type-Specific Synchronization of Neural Activity in FEF with V4 during Attention |
| title_sort | cell type specific synchronization of neural activity in fef with v4 during attention |
| url | http://hdl.handle.net/1721.1/91641 https://orcid.org/0000-0002-5938-4227 |
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