A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

Understanding the principles governing mammalian gene regulation has been hampered by the difficulty in measuring in vivo binding dynamics of large numbers of transcription factors (TF) to DNA. Here, we develop a high-throughput Chromatin ImmunoPrecipitation (HT-ChIP) method to systematically map pr...

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Bibliographic Details
Main Authors: Garber, Manuel, Yosef, Nir, Goren, Alon, Raychowdhury, Raktima, Thielke, Anne, Guttman, Mitchell, Robinson, James, Minie, Brian, Chevrier, Nicolas, Itzhaki, Zohar, Blecher-Gonen, Ronnie, Bornstein, Chamutal, Amann-Zalcenstein, Daniela, Weiner, Assaf, Friedrich, Dennis C., Meldrim, James C., Ram, Oren, Cheng, Christine S., Gnirke, Andreas, Fisher, Sheila, Friedman, Nir, Wong, Bang, Bernstein, Bradley E., Nusbaum, Chad, Hacohen, Nir, Regev, Aviv, Amit, Ido
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/91898
https://orcid.org/0000-0002-9512-9127
https://orcid.org/0000-0001-8567-2049

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