Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

The functional role of pericytes in cancer progression remains unknown. Clinical studies suggest that low numbers of vessel-associated pericytes correlated with a drop in overall survival of patients with invasive breast cancer. Using genetic mouse models or pharmacological inhibitors, pericyte depl...

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Bibliographic Details
Main Authors: Cooke, Vesselina G., LeBleu, Valerie Sandra, Keskin, Doruk, Khan, Zainab, O’Connell, Joyce T., Teng, Yingqi, Duncan, Michael B., Xie, Liang, Maeda, Genta, Vong, Sylvia, Sugimoto, Hikaru, Rocha, Rafael M., Damascena, Aline, Brentani, Ricardo R., Kalluri, Raghu
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier B.V. 2014
Online Access:http://hdl.handle.net/1721.1/91948

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