Steady States and Dynamics of Urokinase-Mediated Plasmin Activation In Silico and In Vitro
Plasmin (PLS) and urokinase-type plasminogen activator (UPA) are ubiquitous proteases that regulate the extracellular environment. Although they are secreted in inactive forms, they can activate each other through proteolytic cleavage. This mutual interplay creates the potential for complex dynamics...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2014
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| Online Access: | http://hdl.handle.net/1721.1/92049 https://orcid.org/0000-0003-1080-4005 https://orcid.org/0000-0001-7387-3572 |