Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

Toll-like receptor (TLR) signaling plays a critical role in innate and adaptive immune responses and must be tightly controlled. TLR4 uses LPS binding protein, MD-2, and CD14 as accessories to respond to LPS. We therefore investigated the presence of an analagous soluble cofactor that might assist i...

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Bibliographic Details
Main Authors: Park, Boyoun, Buti, Ludovico, Lee, Sungwook, Matsuwaki, Takashi, Spooner, Eric, Brinkmann, Melanie M., Nishihara, Masugi, Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2014
Online Access:http://hdl.handle.net/1721.1/92258
https://orcid.org/0000-0002-1090-6071

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