Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast
The epithelial-mesenchymal transition (EMT) has been associated with the acquisition of motility, invasiveness, and self-renewal traits. During both normal development and tumor pathogenesis, this change in cell phenotype is induced by contextual signals that epithelial cells receive from their micr...
Main Authors: | Scheel, Christina, Eaton, Elinor Ng, Chaffer, Christine L., Reinhardt, Ferenc, Kah, Kong-Jie, Bell, George, Guo, Wenjun, Rubin, Jeffrey, Richardson, Andrea L., Weinberg, Robert A., Li, Sophia, Weinberg, Robert A |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2014
|
Online Access: | http://hdl.handle.net/1721.1/92261 https://orcid.org/0000-0002-0895-3557 |
Similar Items
-
Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?
by: Scheel, Christina, et al.
Published: (2018) -
Probing Embryonic Stem Cell Autocrine and Paracrine Signaling Using Microfluidics
by: Voldman, Joel, et al.
Published: (2014) -
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
by: Kojima, Yasushi, et al.
Published: (2011) -
CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms
by: Subramanian, Karthik, et al.
Published: (2014) -
Direct and Indirect Regulators of Epithelial–Mesenchymal Transition–Mediated Immunosuppression in Breast Carcinomas
by: Dongre, Anushka, et al.
Published: (2023)