Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception
Normal brain function requires the dynamic interaction of functionally specialized but widely distributed cortical regions. Long-range synchronization of oscillatory signals has been suggested to mediate these interactions within large-scale cortical networks, but direct evidence is sparse. Here we...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Elsevier
2014
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| Online Access: | http://hdl.handle.net/1721.1/92314 |
| _version_ | 1811093878570221568 |
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| author | Hipp, Joerg F. Engel, Andreas K. Siegel, Markus |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Hipp, Joerg F. Engel, Andreas K. Siegel, Markus |
| author_sort | Hipp, Joerg F. |
| collection | MIT |
| description | Normal brain function requires the dynamic interaction of functionally specialized but widely distributed cortical regions. Long-range synchronization of oscillatory signals has been suggested to mediate these interactions within large-scale cortical networks, but direct evidence is sparse. Here we show that oscillatory synchronization is organized in such large-scale networks. We implemented an analysis approach that allows for imaging synchronized cortical networks and applied this technique to EEG recordings in humans. We identified two networks: beta-band synchronization (∼20 Hz) in a fronto-parieto-occipital network and gamma-band synchronization (∼80 Hz) in a centro-temporal network. Strong perceptual correlates support their functional relevance: the strength of synchronization within these networks predicted the subjects' percept of an ambiguous audiovisual stimulus as well as the integration of auditory and visual information. Our results provide evidence that oscillatory neuronal synchronization mediates neuronal communication within frequency-specific, large-scale cortical networks. |
| first_indexed | 2024-09-23T15:52:08Z |
| format | Article |
| id | mit-1721.1/92314 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:52:08Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/923142022-09-29T16:39:05Z Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception Hipp, Joerg F. Engel, Andreas K. Siegel, Markus Picower Institute for Learning and Memory Siegel, Markus Normal brain function requires the dynamic interaction of functionally specialized but widely distributed cortical regions. Long-range synchronization of oscillatory signals has been suggested to mediate these interactions within large-scale cortical networks, but direct evidence is sparse. Here we show that oscillatory synchronization is organized in such large-scale networks. We implemented an analysis approach that allows for imaging synchronized cortical networks and applied this technique to EEG recordings in humans. We identified two networks: beta-band synchronization (∼20 Hz) in a fronto-parieto-occipital network and gamma-band synchronization (∼80 Hz) in a centro-temporal network. Strong perceptual correlates support their functional relevance: the strength of synchronization within these networks predicted the subjects' percept of an ambiguous audiovisual stimulus as well as the integration of auditory and visual information. Our results provide evidence that oscillatory neuronal synchronization mediates neuronal communication within frequency-specific, large-scale cortical networks. European Union (Grant IST-2005-027268) European Union (Grant NEST-PATH-043457) European Union (Grant HEALTH-F2-2008-200728) German Research Foundation (Grant GRK 1247/1) German Research Foundation (Grant GRK 1247/2) Germany. Federal Ministry of Education and Research (BMBF) (Neuroimage Nord. Grant 01GW0561) 2014-12-16T14:11:47Z 2014-12-16T14:11:47Z 2011-01 2010-11 Article http://purl.org/eprint/type/JournalArticle 08966273 1097-4199 http://hdl.handle.net/1721.1/92314 Hipp, Joerg F., Andreas K. Engel, and Markus Siegel. “Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception.” Neuron 69, no. 2 (January 2011): 387–396. © 2011 Elsevier Inc. en_US http://dx.doi.org/10.1016/j.neuron.2010.12.027 Neuron Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Elsevier Elsevier |
| spellingShingle | Hipp, Joerg F. Engel, Andreas K. Siegel, Markus Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title | Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title_full | Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title_fullStr | Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title_full_unstemmed | Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title_short | Oscillatory Synchronization in Large-Scale Cortical Networks Predicts Perception |
| title_sort | oscillatory synchronization in large scale cortical networks predicts perception |
| url | http://hdl.handle.net/1721.1/92314 |
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