End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot-scale plant used a novel route that incorporated many advantages of continuous-flow processes to produce active pharmaceutical ingredients and the drug prod...

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Bibliographic Details
Main Authors: Mascia, Salvatore, Heider, Patrick L., Zhang, Haitao, Lakerveld, Richard, Benyahia, Brahim, Barton, Paul I., Braatz, Richard D., Cooney, Charles L., Evans, James M. B., Jamison, Timothy F., Jensen, Klavs F., Myerson, Allan S., Trout, Bernhardt L.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2014
Online Access:http://hdl.handle.net/1721.1/92450
https://orcid.org/0000-0002-0828-535X
https://orcid.org/0000-0003-2895-9443
https://orcid.org/0000-0001-7192-580X
https://orcid.org/0000-0002-8601-7799
https://orcid.org/0000-0003-1417-9470
https://orcid.org/0000-0003-4304-3484

Internet

http://hdl.handle.net/1721.1/92450
https://orcid.org/0000-0002-0828-535X
https://orcid.org/0000-0003-2895-9443
https://orcid.org/0000-0001-7192-580X
https://orcid.org/0000-0002-8601-7799
https://orcid.org/0000-0003-1417-9470
https://orcid.org/0000-0003-4304-3484

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