High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization
Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons...
| Main Authors: | , , |
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| Format: | Article |
| Language: | en_US |
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Frontiers Research Foundation
2014
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| Online Access: | http://hdl.handle.net/1721.1/92496 |
| _version_ | 1826202406603456512 |
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| author | Emadi, Nazli Rajimehr, Reza Esteky, Hossein |
| author2 | McGovern Institute for Brain Research at MIT |
| author_facet | McGovern Institute for Brain Research at MIT Emadi, Nazli Rajimehr, Reza Esteky, Hossein |
| author_sort | Emadi, Nazli |
| collection | MIT |
| description | Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons in the inferior temporal cortex of monkeys performing a visual categorization task, we thoroughly explored the relationship between baseline activity, the evoked response, and behavior. Specifically we found that a low-frequency (<8 Hz) oscillation in the spike train, prior and phase-locked to the stimulus onset, was correlated with increased gamma power and neuronal baseline activity. This enhancement of the baseline activity was then followed by an increase in the neural selectivity and the response reliability and eventually a higher behavioral performance. |
| first_indexed | 2024-09-23T12:06:57Z |
| format | Article |
| id | mit-1721.1/92496 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:06:57Z |
| publishDate | 2014 |
| publisher | Frontiers Research Foundation |
| record_format | dspace |
| spelling | mit-1721.1/924962022-10-01T08:15:35Z High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization Emadi, Nazli Rajimehr, Reza Esteky, Hossein McGovern Institute for Brain Research at MIT Rajimehr, Reza Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons in the inferior temporal cortex of monkeys performing a visual categorization task, we thoroughly explored the relationship between baseline activity, the evoked response, and behavior. Specifically we found that a low-frequency (<8 Hz) oscillation in the spike train, prior and phase-locked to the stimulus onset, was correlated with increased gamma power and neuronal baseline activity. This enhancement of the baseline activity was then followed by an increase in the neural selectivity and the response reliability and eventually a higher behavioral performance. Iran National Science Foundation (INSF) 2014-12-24T15:51:49Z 2014-12-24T15:51:49Z 2014-11 2014-06 Article http://purl.org/eprint/type/JournalArticle 1662-5137 http://hdl.handle.net/1721.1/92496 Emadi, Nazli, Reza Rajimehr, and Hossein Esteky. “High Baseline Activity in Inferior Temporal Cortex Improves Neural and Behavioral Discriminability During Visual Categorization.” Front. Syst. Neurosci. 8 (November 3, 2014). en_US http://dx.doi.org/10.3389/fnsys.2014.00218 Frontiers in Systems Neuroscience Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf Frontiers Research Foundation Frontiers Research Foundation |
| spellingShingle | Emadi, Nazli Rajimehr, Reza Esteky, Hossein High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title | High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title_full | High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title_fullStr | High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title_full_unstemmed | High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title_short | High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| title_sort | high baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization |
| url | http://hdl.handle.net/1721.1/92496 |
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