Loss of α-catenin elicits a cholestatic response and impairs liver regeneration

Loss of α-catenin elicits a cholestatic response and impairs liver regeneration

The liver is unique in its capacity to regenerate after injury, during which hepatocytes actively divide and establish cell-cell contacts through cell adhesion complexes. Here, we demonstrate that the loss of α-catenin, a well-established adhesion component, dramatically disrupts liver regeneration....

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Bibliographic Details
Main Authors: Herr, Keira Joann, Tsang, Ying-hung Nicole, Ong, Joanne Wei En, Li, Qiushi, Yap, Lai Lai, Yu, Weimiao, Yin, Hao, Dahlman, James E., Chan, Yee Gek, Bay, Boon Huat, Singaraja, Roshni, Kotelianski, Victor E., Viasnoff, Virgile, Thiery, Jean Paul, Bogorad, Roman, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/1721.1/92572
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793

Internet

http://hdl.handle.net/1721.1/92572
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0001-6898-3793

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