Mass Transport and Reactions in the Tube-in-Tube Reactor
The tube-in-tube reactor is a convenient method for implementing gas/liquid reactions on the microscale, in which pressurized gas permeates through a Teflon AF-2400 membrane and reacts with substrates in liquid phase. Here we present the first quantitative models for analytically and numerically com...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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American Chemical Society (ACS)
2015
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| Online Access: | http://hdl.handle.net/1721.1/92948 https://orcid.org/0000-0001-7192-580X https://orcid.org/0000-0001-6153-9753 |
| _version_ | 1811082603181113344 |
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| author | Yang, Lu Jensen, Klavs F. |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Yang, Lu Jensen, Klavs F. |
| author_sort | Yang, Lu |
| collection | MIT |
| description | The tube-in-tube reactor is a convenient method for implementing gas/liquid reactions on the microscale, in which pressurized gas permeates through a Teflon AF-2400 membrane and reacts with substrates in liquid phase. Here we present the first quantitative models for analytically and numerically computing gas and substrate concentration profiles within the tube-in-tube reactor. The model accurately predicts mass transfer performance in good agreement with experimental measurement. The scaling behavior and reaction limitations of the tube-in-tube reactor are predicted by modeling and compared with gas/liquid micro- and minireactors. The presented model yields new insights into the scalability and applicability of the tube-in-tube reactor. |
| first_indexed | 2024-09-23T12:06:02Z |
| format | Article |
| id | mit-1721.1/92948 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:06:02Z |
| publishDate | 2015 |
| publisher | American Chemical Society (ACS) |
| record_format | dspace |
| spelling | mit-1721.1/929482022-09-28T00:06:41Z Mass Transport and Reactions in the Tube-in-Tube Reactor Yang, Lu Jensen, Klavs F. Massachusetts Institute of Technology. Department of Chemical Engineering Jensen, Klavs F. Yang, Lu Jensen, Klavs F. The tube-in-tube reactor is a convenient method for implementing gas/liquid reactions on the microscale, in which pressurized gas permeates through a Teflon AF-2400 membrane and reacts with substrates in liquid phase. Here we present the first quantitative models for analytically and numerically computing gas and substrate concentration profiles within the tube-in-tube reactor. The model accurately predicts mass transfer performance in good agreement with experimental measurement. The scaling behavior and reaction limitations of the tube-in-tube reactor are predicted by modeling and compared with gas/liquid micro- and minireactors. The presented model yields new insights into the scalability and applicability of the tube-in-tube reactor. Novartis-MIT Center for Continuous Manufacturing 2015-01-16T19:17:23Z 2015-01-16T19:17:23Z 2013-06 2013-04 Article http://purl.org/eprint/type/JournalArticle 1083-6160 1520-586X http://hdl.handle.net/1721.1/92948 Yang, Lu, and Klavs F. Jensen. “Mass Transport and Reactions in the Tube-in-Tube Reactor.” Org. Process Res. Dev. 17, no. 6 (June 21, 2013): 927–933. https://orcid.org/0000-0001-7192-580X https://orcid.org/0000-0001-6153-9753 en_US http://dx.doi.org/10.1021/op400085a Organic Process Research & Development Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Chemical Society (ACS) Prof. Jensen via Erja Kajosalo |
| spellingShingle | Yang, Lu Jensen, Klavs F. Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title | Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title_full | Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title_fullStr | Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title_full_unstemmed | Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title_short | Mass Transport and Reactions in the Tube-in-Tube Reactor |
| title_sort | mass transport and reactions in the tube in tube reactor |
| url | http://hdl.handle.net/1721.1/92948 https://orcid.org/0000-0001-7192-580X https://orcid.org/0000-0001-6153-9753 |
| work_keys_str_mv | AT yanglu masstransportandreactionsinthetubeintubereactor AT jensenklavsf masstransportandreactionsinthetubeintubereactor |