Design of a robust, intuitive piston interface for a needle free injection system

Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014.

Bibliographic Details
Main Author: Nawrot, Michael Thomas
Other Authors: Ian W. Hunter.
Format: Thesis
Language:eng
Published: Massachusetts Institute of Technology 2015
Subjects:
Online Access:http://hdl.handle.net/1721.1/93008
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author Nawrot, Michael Thomas
author2 Ian W. Hunter.
author_facet Ian W. Hunter.
Nawrot, Michael Thomas
author_sort Nawrot, Michael Thomas
collection MIT
description Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014.
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spelling mit-1721.1/930082019-04-12T22:04:37Z Design of a robust, intuitive piston interface for a needle free injection system Nawrot, Michael Thomas Ian W. Hunter. Massachusetts Institute of Technology. Department of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering. Mechanical Engineering. Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014. Cataloged from PDF version of thesis. Includes bibliographical references (pages 193-195). The MIT BioInstrumentation Lab's linear Lorentz force actuator based needle free injection system has been shown to have numerous benefits over needle-based and other needle-free drug delivery systems in a research environment. While the device has been used extensively on post mortem tissue and live animals, its use on humans has been restricted in large part because of an ineffective drug delivery ampoule interface which compromises sterility. A new ampoule interface has been developed to allow sterility to be maintained, while also improving robustness against manufacturing tolerances and user error. The new ampoule interface has been tested and compared to the previous ampoule interface and shown to have comparable performance during normal use, while also surviving misuse. An intuitive user interface has also been developed which eases the process of mounting and dismounting ampoules. by Michael Thomas Nawrot. S.M. 2015-01-20T17:53:19Z 2015-01-20T17:53:19Z 2014 2014 Thesis http://hdl.handle.net/1721.1/93008 899209172 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 195 pages application/pdf Massachusetts Institute of Technology
spellingShingle Mechanical Engineering.
Nawrot, Michael Thomas
Design of a robust, intuitive piston interface for a needle free injection system
title Design of a robust, intuitive piston interface for a needle free injection system
title_full Design of a robust, intuitive piston interface for a needle free injection system
title_fullStr Design of a robust, intuitive piston interface for a needle free injection system
title_full_unstemmed Design of a robust, intuitive piston interface for a needle free injection system
title_short Design of a robust, intuitive piston interface for a needle free injection system
title_sort design of a robust intuitive piston interface for a needle free injection system
topic Mechanical Engineering.
url http://hdl.handle.net/1721.1/93008
work_keys_str_mv AT nawrotmichaelthomas designofarobustintuitivepistoninterfaceforaneedlefreeinjectionsystem