The mechanism and function of pervasive noncoding transcription in the mammalian genome

The mechanism and function of pervasive noncoding transcription in the mammalian genome

Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, 2014.

Bibliographic Details
Main Author:	Wu, Xuebing, Ph. D. Massachusetts Institute of Technology
Other Authors:	Phillip A. Sharp and Christopher B. Burge.
Format:	Thesis
Language:	eng
Published:	Massachusetts Institute of Technology 2015
Subjects:	Computational and Systems Biology Program.
Online Access:	http://hdl.handle.net/1721.1/93042

Similar Items

Pervasive degeneracy and epistasis in a protein-protein interface
by: Podgornaia, Anna Igorevna
Published: (2015)

Genome regulation by long noncoding RNAs
by: Engreitz, Jesse M. (Jesse Michael)
Published: (2016)

Mechanical characterization of mammalian brain tissue and energy dissipative polymers
by: Qing, Bo, Ph. D. Massachusetts Institute of Technology
Published: (2019)

Editing DNA Methylation in the Mammalian Genome
by: Liu, X. Shawn, et al.
Published: (2018)

Linking sequence to function in microbial genomics
by: Spencer, Sarah Jean
Published: (2018)

Statistically inferring the mechanisms of phage-host interactions
by: Yang, Joy,Ph.D.(Joy Yu)Massachusetts Institute of Technology.
Published: (2019)

DNA methylation in early mammalian development
by: Chan, Michelle M. (Michelle Mei Wah)
Published: (2013)

High-resolution interrogation of functional elements in the noncoding genome
by: Fontanillas, P., et al.
Published: (2017)

Evolutionary and structural signatures of protein-coding function : synonymous acceleration, read-through, and structural impact of mutations
by: Wolf, Maxim,Ph. D.(Maxim Y.)Massachusetts Institute of Technology.
Published: (2020)

Exploring the regulatory roles of microRNAs in mammalian development
by: Zheng, Grace Xinying
Published: (2010)

Architectures of the third cloud : distributed, mobile, and pervasive systems design
by: Gauthier, David, S.M. Massachusetts Institute of Technology
Published: (2010)

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain
by: Kleaveland, Benjamin, et al.
Published: (2020)

c-Myc regulates transcriptional pause release and is a global amplifier of transcription
by: Lin, Charles Yang
Published: (2013)

Pervasive Synaptic Branch Removal in the Mammalian Neuromuscular System at Birth
by: Tapia, Juan C., et al.
Published: (2014)

Epigenetic and post-transcriptional regulation of gene expression in pluripotent stem cells, differentiation and metastasis
by: Cheng, Wu Albert
Published: (2014)

Transcriptional regulation and genome structure
by: Weintraub, Abraham S. (Abraham Selby)
Published: (2018)

Genome organization in transcriptional regulation
by: Li, Charles H.
Published: (2021)

Microbial adaptation, differentiation, and community structure
by: Friedman, Jonathan, Ph. D. Massachusetts Institute of Technology
Published: (2013)

Coordination of cellular force-generation during Drosophila ventral furrow formation
by: Xie, Shicong, Ph. D. Massachusetts Institute of Technology
Published: (2016)

Computational modeling techniques for biological network productivity increases : optimization and rate-limiting reaction detection
by: Cui, Yuanyuan, Ph.D. Massachusetts Institute of Technology
Published: (2013)

Mechanics and dynamics of living mammalian cytoplasm
by: Gupta, Satish Kumar, Ph.D. Massachusetts Institute of Technology
Published: (2017)

Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress
by: Kuznetsov, Vladimir Andreevich, et al.
Published: (2015)

Transcriptional and structural control of cell identity genes
by: Fan, Zi Peng
Published: (2015)

Targeting and function of mammalian microRNAs
by: Farh, Kyle Kai-How
Published: (2014)

Divergent Transcription: A Driving Force for New Gene Origination?
by: Sharp, Phillip A., et al.
Published: (2017)

Unfolding genome organization in interphase
by: Abdennur, Nezar(Nezar Alexander)
Published: (2019)

TATA binding protein and associated factors in mammalian transcription : characterization of the B-TFIID activity
by: Meyers, Rachel Ellen
Published: (2006)

Whole genome regulatory variant evaluation for transcription factor binding
by: Zeng, Haoyang, Ph.D. Massachusetts Institute of Technology
Published: (2015)

The functional microRNA landscape of mammalian development
by: Ravi, Arvind
Published: (2011)

Novel phylogenetic approaches to problems in microbial genomics
by: David, Lawrence A. (Lawrence Anthony)
Published: (2011)

Dynamics of DNA methylation and genomic imprinting in arabidopsis
by: Picard, Colette Lafontaine.
Published: (2019)

Identifying a transcriptional signature for cell sensitivity to the cancer chemotherapy agent, BCNU
by: Valiathan, Chandni Rajan
Published: (2011)

Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains
by: Yeo, Samuel Jianjie, et al.
Published: (2023)

Deciphering genetic associations using genome-wide epigenomics approaches
by: Wang, Xinchen, Ph. D. Massachusetts Institute of Technology
Published: (2017)

Genomic signatures of sex, selection and speciation in the microbial world
by: Shapiro, B. Jesse (Benjamin Jesse)
Published: (2011)

Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
by: Goff, Loyal A., et al.
Published: (2016)

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
by: Hung, Tiffany, et al.
Published: (2014)

Genetic networks controlled by the bacterial replication initiator and transcription factor DnaA in Bacillus subtilis
by: Washington, Tracy (Tracy Alexander)
Published: (2014)

Genome-wide analysis of transcription factors and chromatin in S. cerevisiae
by: Wyrick, John J. (John Jason), 1974-
Published: (2005)

Chromatin and transcriptional regulators act in a cascade to establish a bilateral asymmetry of the C. elegans nervous system
by: Nakano, Shunji, Ph. D. Massachusetts Institute of Technology
Published: (2011)