Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity
Anaerobic degradation of the environmental pollutant toluene is initiated by the glycyl radical enzyme benzylsuccinate synthase (BSS), which catalyzes the radical addition of toluene to fumarate, forming benzylsuccinate. We have determined crystal structures of the catalytic α-subunit of BSS with it...
Main Authors: | Funk, Michael Andrew, Judd, Evan T., Marsh, E. Neil G., Elliott, Sean J., Drennan, Catherine L |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2015
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Online Access: | http://hdl.handle.net/1721.1/93788 https://orcid.org/0000-0001-5486-2755 |
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