Differential requirement for NMDAR activity in SAP97 -mediated regulation of the number and strength of glutamatergic AMPAR-containing synapses
PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we s...
Main Authors: | Liu, Mingna, Lewis, Laura D., Shi, Rebecca D., Xu, Weifeng, Brown, Emery Neal |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
American Physiological Society
2015
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Online Access: | http://hdl.handle.net/1721.1/93904 https://orcid.org/0000-0001-6888-5448 https://orcid.org/0000-0003-2668-7819 https://orcid.org/0000-0001-7060-0288 https://orcid.org/0000-0003-0096-2288 |
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