Synthesis and Application of Palladium Precatalysts that Accommodate Extremely Bulky Di-tert-butylphosphino Biaryl Ligands

A series of palladacyclic precatalysts that incorporate electron-rich di-tert-butylphosphino biaryl ligands is reported. These precatalysts are easily prepared, and their use provides a general means of employing bulky ligands in palladium-catalyzed cross-coupling reactions. The application of these...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Bruno, Nicholas C., Buchwald, Stephen Leffler
अन्य लेखक: Massachusetts Institute of Technology. Department of Chemistry
स्वरूप: लेख
भाषा:en_US
प्रकाशित: American Chemical Society (ACS) 2015
ऑनलाइन पहुंच:http://hdl.handle.net/1721.1/93913
https://orcid.org/0000-0003-3875-4775
विवरण
सारांश:A series of palladacyclic precatalysts that incorporate electron-rich di-tert-butylphosphino biaryl ligands is reported. These precatalysts are easily prepared, and their use provides a general means of employing bulky ligands in palladium-catalyzed cross-coupling reactions. The application of these palladium sources to various C–N and C–O bond-forming processes is also described.