Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angiosa...

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Main Authors: Tonomura, Noriko, Elvers, Ingegerd, Thomas, Rachael, Megquier, Kate, Turner-Maier, Jason, Howald, Cedric, Sarver, Aaron L., Swofford, Ross, Frantz, Aric M., Ito, Daisuke, Mauceli, Evan, Arendt, Maja, Noh, Hyun Ji, Koltookian, Michele, Biagi, Tara, Fryc, Sarah, Williams, Christina, Avery, Anne C., Kim, Jong-Hyuk, Barber, Lisa, Burgess, Kristine, Karlsson, Elinor K., Azuma, Chieko, Modiano, Jaime F., Breen, Matthew, Lindblad-Toh, Kerstin, Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2015
Online Access:http://hdl.handle.net/1721.1/94603

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