Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids

Synthesis and Anticancer Activity of All Known (−)-Agelastatin Alkaloids

The full details of our enantioselective total syntheses of (−)-agelastatins A–F (1–6), the evolution of a new methodology for synthesis of substituted azaheterocycles, and the first side-by-side evaluation of all known (−)-agelastatin alkaloids against nine human cancer cell lines are described. Ou...

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Bibliographic Details
Main Authors: Han, Sunkyu, Siegel, Dustin S., Morrison, Karen C., Hergenrother, Paul J., Movassaghi, Mohammad
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2015
Online Access:http://hdl.handle.net/1721.1/95515
https://orcid.org/0000-0003-3080-1063

Internet

http://hdl.handle.net/1721.1/95515
https://orcid.org/0000-0003-3080-1063

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