Controlling multipotent stromal cell migration by integrating “course-graining” materials and “fine-tuning” small molecules via decision tree signal-response modeling
Biomimetic scaffolds have been proposed as a means to facilitate tissue regeneration by multi-potent stromal cells (MSCs). Effective scaffold colonization requires a control of multiple MSC responses including survival, proliferation, differentiation, and migration. As MSC migration is relatively un...
Main Authors: | Wu, Shan, Wells, Alan, Griffith, Linda G., Lauffenburger, Douglas A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
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Online Access: | http://hdl.handle.net/1721.1/95816 https://orcid.org/0000-0002-1801-5548 |
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