Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

Human mesenchymal stem cells (hMSCs) are therapeutically useful cells that are typically expanded in vitro on stiff substrata before reimplantation. Here we explore MSC mechanical and structural changes via atomic force microscopy and optical stretching during extended passaging, and we demonstrate...

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Bibliographic Details
Main Authors: Maloney, John M., Nikova, Dessy, Lautenschläger, Franziska, Clarke, Emer, Langer, Robert, Guck, Jochen, Van Vliet, Krystyn J.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2015
Online Access:http://hdl.handle.net/1721.1/96041
https://orcid.org/0000-0001-5735-0560
https://orcid.org/0000-0002-6853-811X
https://orcid.org/0000-0003-4255-0492