Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation

A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture ( Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.

Bibliographic Details
Main Authors: Chou, Song, Chu, Pat, Hwang, William, Lodish, Harvey F
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2015
Online Access:http://hdl.handle.net/1721.1/96082
https://orcid.org/0000-0002-7029-7415
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author Chou, Song
Chu, Pat
Hwang, William
Lodish, Harvey F
author2 Massachusetts Institute of Technology. Department of Biology
author_facet Massachusetts Institute of Technology. Department of Biology
Chou, Song
Chu, Pat
Hwang, William
Lodish, Harvey F
author_sort Chou, Song
collection MIT
description A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture ( Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.
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spelling mit-1721.1/960822022-10-03T09:08:49Z Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation Chou, Song Chu, Pat Hwang, William Lodish, Harvey F Massachusetts Institute of Technology. Department of Biology Whitehead Institute for Biomedical Research Chou, Song Lodish, Harvey F. A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture ( Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically. 2015-03-19T16:32:25Z 2015-03-19T16:32:25Z 2010-10 Article http://purl.org/eprint/type/JournalArticle 19345909 http://hdl.handle.net/1721.1/96082 Chou, Song, Pat Chu, William Hwang, and Harvey Lodish. “Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation.” Cell Stem Cell 7, no. 4 (October 2010): 427–428. © 2010 Elsevier B.V. https://orcid.org/0000-0002-7029-7415 en_US http://dx.doi.org/10.1016/j.stem.2010.09.001 Cell Stem Cell Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Elsevier B.V. Elsevier
spellingShingle Chou, Song
Chu, Pat
Hwang, William
Lodish, Harvey F
Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title_full Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title_fullStr Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title_full_unstemmed Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title_short Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
title_sort expansion of human cord blood hematopoietic stem cells for transplantation
url http://hdl.handle.net/1721.1/96082
https://orcid.org/0000-0002-7029-7415
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