Expansion of Human Cord Blood Hematopoietic Stem Cells for Transplantation
A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture ( Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.
Main Authors: | Chou, Song, Chu, Pat, Hwang, William, Lodish, Harvey F |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Elsevier B.V.
2015
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Online Access: | http://hdl.handle.net/1721.1/96082 https://orcid.org/0000-0002-7029-7415 |
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